Neural Stem Cell Injection Into Spine

Stem Cells burst into the public spotlight several year’s ago with promises to cure almost any disease or injury, including brain injury.  Unfortunately, progress has been slow, partly because of complex ethical and regulatory issues.   In China (and other countries such as Mexico, India, Turkey, Russia), there are hospitals that have been using stem cells to actively treat humans.

This is obviously very interesting.   As of January 2012 BRIGHT does not have any first hand knowledge as to the safety or effectiveness of this treatment.  However, we are very interested to be contacted by anyone who has undergone treatment at this facility or similar around the world.

Also of note is that as of January 2012 China has ordered a halt to all unapproved stem cell treatments.  However, it is reported that hospitals that are run by the military or police forces are not under the control of the same regulatory bodies and therefore are not effected by the ban.   More information on this can be found here:

Beijing bans stem cell studies

Unapproved stem cell treatments stopped in China

We have found one website is clearly commercial in nature.  It describes improvements in vague terms.  It acknowledges the risks, but does not attempt to quantify the risks or the improvements.

Here is the contact information for the program as well as the website.    Again, we would be very interested to learn of anyone with first hand knowledge of treatment by Neural Stem Cell Injection directly Into Spine, or other similar treatments.

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Address: China Stem Cells Medical Center #198 Fengbao Road, Fengtai District, Beijing, 100160, People, s Republic of China
Stem Cells Treatment of Cerebral Palsy

 We have recently developed a comprehensive program for Cerebral Palsy patients combining both nerve stem cell activation and stimulation treatment, and stem cells injections. This combined treatment has so far proven itself to be the most effective means to achieving a high level of recovery. 

The treatment includes stem cell implantation, a “cocktail” of medications and brain nutrition materials given through IV, biofeedback treatment and comprehensive rehabilitation.

By employing all of the above methods we can maximally improve functions such as sensibility, mobility, language and intelligence. 

The key to the success of this treatment method is the overall customized treatment regimen for each patient.

Self Stem Cells Activation and Proliferation:

Using a non-invasive procedure, through daily IV of an individually customized cocktail of neurotrophic medications, we activate the patient´´s own stem cells and as a result, turn these cells into nerve precursor cells. These cells have signalization and migrate to lesions along the nerve developing-chord.

Neural Stem Cells Injections:

Neural stem cells extracted from a fetus have the advantage of already being specialized naturally into neural cells and therefore there is no need to induce them into becoming neural cells by artificial means.

We offer a safe stem cell implantation procedure for Cerebral Palsy patients. The procedure includes: Sub-arachnoid Surgery, spinal cord fluid stem cell injections, and an injection through a lumbar puncture into the spinal cord fluid.

We use this technique in the following cases:

1. The patient cannot cooperate properly for going through sterotaxios brain surgery.

2. The target in the brain is not clear enough to use the brain injection.

This procedure takes between 5 and 10 minutes. It is a simple and safe procedure that has almost no side effects or risks. This procedure takes place in the operating room and is performed by stem cell specialists.

Typically, 3 or 4 injections of 5 million cells each are given to the patient.

 

Rehabilitation:

Rehabilitation therapy is a very necessary part of the whole treatment regimen. In the past 20 years nerve system rehabilitation, in terms of motor control theory, has been greatly developed. The research results indicate that brain injury is an anatomical injury and it does not necessarily mean functional loss. Modern Nerve Development Theory (NDT) focuses on what functions remain and what functions can be regained through treatment and/or training.

 

The adult stem cell mobilization technique we use is combined with signal induction in the rehabilitation training procedure which can significantly improve brain function.

 

In our Rehabilitation Center we use different kinds of rehabilitation methods including: Physical Therapy, Occupational Therapy and Speech Therapy.

 

The Procedures:

Self stem cell activation and proliferation program

This program usually requires a 4 to 5 weeks staying in the Hospital.

1. Upon arrival at the hospital, you will be given standard tests to check your health and the details of your condition. A thorough evaluation of the neurological function and understanding of the lesion or pathological change in the brain tissues will be established by the medical team.

2. According to your condition a medical plan will be designed for Self Stem Cell Original Activation and Proliferation treatment. Then, to drive off the trigger factors of the stroke, we will treat the blood vessel wall, the blood ingredients and the blood flow, improving the brain microenvironment to help the stem cells proliferate.

3. The self activation and proliferation treatment will then start. Based on the Neuro-endocrine Immune Network Theory, we treat the patient by “waking up” the sleeping stem cells through oral medication. We use different medications during different processes (proliferation-inducement-differentiation), the medications are always adjusted and combined; therefore, we call it a “cocktail treatment.”

4. Throughout the treatment period we will be following up and evaluating your neurological function and improvement.

5. After the first treatment cycle is complete, 2 to 5 months of rest are recommended before starting the second treatment

Stem Cell Implantation through the Cerebral Spinal Fluid (Lumbar Puncture)

Most Cerebral Palsy patients have global brain damage. That is why we recommend doing the stem cells implantation through the spinal cord fluid. Through the CSF the stem cells will migrate to the damaged areas in the brain. This procedure is short and simple and done with local anesthesia.

In order to prevent even the minor risk of infection and maintain a strictly sterile environment, the procedure is done in the operating room by our doctors only.

Side effects:

The procedure can cause minor side effects for 2 to 3 days after the operation including fever, headaches, dizziness and fatigue. These side effects are expected and should not alarm or concern you. Many patients do not suffer any side effects at all.

Treatment period:

The recommended time period for the treatment is 4 to five weeks, but there should be improvement after the first month. The patient can decide whether or not to continue with the second month´´s treatment at the end of the first month.

Written by Dr. Like Wu and Dr. Xiaojuan Wang

What are Neural Stem Cells?

Neural Stem cells are self-regenerating, multipotent cells, found in the human brain which have the potential to differentiate into three major cell types: nerve cells (neurons), astrocytes and oligodendrocytes, and to self renew sufficiently to provide adequate number of cells in the brain.

When brain cells are damaged or are dying, due to a disease or an injury, fetal stem cells are the best known source for human neural stem cells.

Since most brain injuries, stroke, degenerative diseases and Demyelinating disorders affect several areas in the brain and not only one, the most effective and safe procedure to deliver neural stem cell into the brain is via a Lumbar Puncture (also called Spinal Tap): a spinal injection in the lumbar area (lower back) into the CSF (Cerebral Spinal Fluid).

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